Ausrichter DL-Acetyl Methionine Injection 50mL

Ausrichter DL-Acetyl Methionine is an injectable amino acid preparation registered for use as supportive therapy in the treatment of liver disease in horses, cattle, sheep, goats, pigs, dogs and cats.

Each millilitre contains 200mg of acetyl-DL-methionine. Methionine is a sulphur-containing essential amino acid involved in normal protein synthesis and metabolic processes. This injectable formulation should be used as part of a veterinary treatment program following appropriate diagnosis and assessment of liver function.

Veterinary applications:

• Supportive therapy in the treatment of liver disease

• Injectable source of acetyl-DL-methionine

• Registered for horses, cattle, sheep, goats, pigs, dogs and cats

• Administered by slow intramuscular injection

• Repeat treatment may be given after one week or as directed by a veterinarian

• Nil meat and milk withholding period

• 50mL multidose vial

Active constituent:

Acetyl-DL-methionine 200mg/mL.

Directions for use:

Administer by slow intramuscular injection.

• Horses, cattle, sheep, goats and pigs: 10mL per 100kg bodyweight

• Dogs: 10mL per 20kg bodyweight

• Cats: 1mL per kg bodyweight

Repeat after one week or as directed by a veterinarian.

Intramuscular injection may cause some discomfort. The registered product information states that the required dose may be diluted with sterile water using twice the volume of sterile water to the injection dose. This procedure should only be undertaken by, or under the direction of, a veterinarian.

Important:

This is an injectable veterinary product. Diagnosis of liver disease, calculation of the appropriate dose and administration should be undertaken by a veterinarian or suitably trained person acting under veterinary direction.

Do not administer intravenously or subcutaneously unless specifically directed by a veterinarian under applicable prescribing provisions. The Australian registered direction is slow intramuscular injection.

Withholding periods:

• Meat: Nil

• Milk: Nil

• Export slaughter interval: Nil

• Racing: Nil manufacturer-stated withholding period; however, the manufacturer recommends suspending administration for 48 hours before racing

Always check the rules of the relevant racing or competition authority before use.

Presentation:

50mL multidose vial.

Storage:

Store below 25°C and protect from light.

Disposal:

Dispose of the empty container in accordance with the label directions. Place used needles and other sharps immediately into an appropriately labelled sharps container.

APVMA Approval Number:

36730/50mL/0108.

For animal treatment only. Keep out of reach of children. Always read the label and use only as directed.

Frequently Asked Questions

What is Ausrichter DL-Acetyl Methionine used for?

It is registered as supportive therapy in the treatment of liver disease in horses, cattle, sheep, goats, pigs, dogs and cats.

What is the active ingredient?

Each millilitre contains 200mg of acetyl-DL-methionine, a derivative of the essential amino acid methionine.

Is this a nutritional supplement or veterinary injection?

It is an injectable veterinary product. It should be used as part of a veterinary treatment program following appropriate diagnosis and assessment.

How is it administered in Australia?

The Australian registered direction is administration by slow intramuscular injection.

Can it be administered intravenously?

The Australian product information specifies slow intramuscular injection. Do not use another administration route unless specifically directed by a veterinarian under applicable prescribing provisions.

What is the dose for horses?

The registered dose for horses is 10mL per 100kg bodyweight. A veterinarian should calculate and administer the appropriate total dose for the individual horse.

How frequently can treatment be repeated?

The product information states that treatment may be repeated after one week or as directed by a veterinarian.

Can the injection be painful?

Intramuscular administration may cause some discomfort. The product information includes a dilution option using sterile water, but preparation and administration should be undertaken only by, or under the direction of, a veterinarian.

Does it replace diagnosis or treatment of the underlying liver disease?

No. Liver disease can have several causes and requires veterinary diagnosis. This product is registered as supportive therapy and does not replace investigation or treatment of the underlying condition.

What signs may indicate liver disease in a horse?

Possible signs can include reduced appetite, weight loss, jaundice, behavioural or neurological changes and photosensitisation. These signs are not specific to liver disease and require prompt veterinary assessment.

What are the withholding periods?

The registered meat and milk withholding periods and export slaughter interval are nil. The manufacturer lists a nil racing withholding period but recommends suspending administration for 48 hours before racing. Always check the applicable authority’s current rules.

How should the vial be stored?

Store below 25°C and protect it from light. Follow the label instructions for maintaining vial sterility and use after opening.

How should used needles be discarded?

Place used needles and other sharps immediately into an appropriately labelled sharps container. Never dispose of loose needles in general waste.