Articular cartilage synthesis and turnover occurs naturally in healthy joints of both young and adult horses. Osteoarthritis can develop when the balance between cartilage turnover and cartilage synthesis is lost. Such imbalances can occur at any age and can be a result of normal joint stress (daily wear and ageing) or abnormal joint stress (high impact or load bearing exercise, injury or nutritional related problems.)
- Articular cartilage is a complex matrix of hyaluronic acid (HA) and proteoglycans (PGs). HA is an essential component of synovial (joint) fluid which acts to lubricate cartilage allowing smooth, frictionless movement of the joint. Glycosaminoglycans (GAG's) are a mojor compenent of PG's.
- Within the cartilage matrix, HA and PG's interact to form even larger molecules which are "hydrophilic", ie they hold large volumes of water. This attraction to water and high concentrations of HA and PG's give healthy cartilage its ability to absorb impact during any exercise and resist wear.
- Glucosamine is the key building block of HA, GAG's and PGs.
- Research shows that oral supplementation with glucosamine sulphate may be beneficial to the synthesis of HA, GAG's and PG's, helping to maintain the balance of cartilage turnover and cartilage synthesis.
- Chondroitin sulphate is the main type of GAG found in PG's. In young, healthy cartilage, Chondroitin-4-Sulphate is the common form of this GAG. It is one of the key components that gives cartilage its ability to absorb impact and resist wear.
- Studies suggest that oral supplementation with low molecular weight chondroitin-4-sulphate may assist pre-existing joint related problems by preventing the breakdown of healthy cartilage matrix by enzymes released from damaged tissues after injury.
Equine Joint Support Formula 2 is manufacturered using high grade co-crystallised glucosamine sulphate and low molecular weight chondroitin-4-sulphate. The glucosamine is extracted from crustacean shells as glucosamine sulphate, considered to be a more bioactive form of glucosamine than glucosamine HCl.
The chondroitin sulphate in Joint Support Formula 2 is of a low molecular weight to ensure its bioavailability.
Directions for Use:
One level 25g scoop contains approximately 5g of Glucosamine and 1.5g of Chondroitin sulphate.
Initial Administration: 50g (2 scoops) per day, mixed with feed for 2 - 4 weeks.
Ongoing Maintenance: 25g (1 scoop) per day mixed with the feed.
Consult your veterinarian for additional dosage recommendations. During times of heavy competition, training, injury or convalescence, up to 100g (4 scoops) may be administered per day.
Active Constituents (per kg):
200g Glucosamine sulphate
60g Chondroitin sulphate.
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